Husniye Kantarci
- Assistant Professor
- Neuroscience
Contact Information
Biography
Dr. Husniye Kantarci is an Assistant Professor in the Department of Neuroscience at the University of Texas at Austin. Originally from Antakya, Turkiye, Husniye pursued her undergraduate studies in Molecular Biology and Genetics at Bogazici University in Istanbul. Her interest in neural development began in Dr. Bruce Riley’s lab at Texas A&M University, where she studied extracellular signals in the development of Stato-Acoustic Ganglion neurons during her PhD. For her postdoctoral research, she joined Dr. Brad Zuchero’s lab at Stanford University, investigating how glial signals regulate neural development and excitability.
Husniye has earned several accolades for her research, including the Lawrence S. Dillon Distinguished Graduate Student Award for Excellence in Research and Teaching from Texas A&M University, the Walter V. and Idun Berry Postdoctoral Fellowship, the Stanford School of Medicine Dean’s Postdoctoral Fellowship, the Stanford ChEM-H Postdocs at the Interface Postdoctoral Fellowship, and the Jump Start Award for Excellence in Research from Stanford University. She has also received various travel and best oral presentation awards throughout her career. Most recently, she was honored to receive the 2024 NARSAD Young Investigator Grant from the Brain & Behavior Research Foundation.
Research
During her postdoc, Husniye and her colleagues discovered that Schwann cells secrete PGE2, which induces excitability in sensory neurons by upregulating voltage-gated sodium channels. Her lab aims to investigate several exciting research directions, including how glial-derived PGE2 induces neural excitability, the role of glial cells in promoting neural diversity in the PNS, the glial regulation of normal excitability in the brain, and the role of aberrant glial-derived PGE2 on neurological and neurodevelopmental diseases.
Fields of Interest
- Molecular Biology, Genetics & Genomics
- Electrophys, Optogenetics & Chemogenetics
- Optical Imaging
- Cellular/Molecular/Structure
- Cognition/Sensory Systems
Centers and Institutes
- Institute for Neuroscience
Publications
Schwann cell-secreted PGE2 promotes sensory neuron excitability during development
Kantarci H, Elvira PD, Thottumkara AP, O’Connell EM, Iyer M, Donovan LJ, Dugan MQ, Ambiel N, Granados A, Zeng H, Saw NL, Brosius Lutz A, Sloan SA, Gray EE, Tran KV, Vichare A, Yeh AK, Münch AE, Huber M, Agrawal A, Morri M, Zhong H, Shamloo M, Anderson TA, Tawfik VL, Du Bois J, Zuchero JB. Cell. 2024 Aug 6:S0092-8674(24)00827-4. doi: 10.1016/j.cell.2024.07.033. Epub ahead of print. PMID: 39142281.
Oligodendrocyte calcium signaling promotes actin-dependent myelin sheath extension
Iyer M, Kantarci H, Cooper MH, Ambiel N, Novak SW, Andrade LR, Lam M, Jones G, Münch AE, Yu X, Khakh BS, Manor U, Zuchero JB. Nat Commun. 2024 Jan 4;15(1):265. doi: 10.1038/s41467-023-44238-3. PMID: 38177161; PMCID: PMC10767123.
Focused ultrasound-induced inhibition of peripheral nerve fibers in an animal model of acute pain
Anderson TA, Pacharinsak C, Vilches-Moure J, Kantarci H, Zuchero JB, Butts-Pauly K, Yeomans D. Reg Anesth Pain Med. 2023 Sep;48(9):462-470. doi: 10.1136/rapm-2022-104060. Epub 2023 Feb 23. PMID: 36822815; PMCID: PMC11233103.
CNS myelination requires VAMP2/3-mediated membrane expansion in oligodendrocytes
Lam M, Takeo K, Almeida RG, Cooper MH, Wu K, Iyer M, Kantarci H, Zuchero JB. Nat Commun. 2022 Sep 23;13(1):5583. doi: 10.1038/s41467-022-33200-4. PMID: 36151203; PMCID: PMC9508103.
Label-free optical detection of bioelectric potentials using electrochromic thin films
Alfonso FS, Zhou Y, Liu E, McGuire AF, Yang Y, Kantarci H, Li D, Copenhaver E, Zuchero JB, Müller H, Cui B. Proc Natl Acad Sci U S A. 2020 Jul 21;117(29):17260-17268. doi: 10.1073/pnas.2002352117. Epub 2020 Jul 6. PMID: 32632007; PMCID: PMC7382226.
Kantarci H, Gou Y, Riley BB. Elife. 2020 Apr 27;9:e56301. doi: 10.7554/eLife.56301. PMID: 32338604; PMCID: PMC7253172.
Spemann organizer gene Goosecoid promotes delamination of neuroblasts from the otic vesicle
Kantarci H, Gerberding A, Riley BB. Proc Natl Acad Sci U S A. 2016 Nov 1;113(44):E6840-E6848. doi: 10.1073/pnas.1609146113. Epub 2016 Oct 19. PMID: 27791112; PMCID: PMC5098670.
Kantarci H, Edlund RK, Groves AK, Riley BB. PLoS Genet. 2015 Mar 17;11(3):e1005037. doi: 10.1371/journal.pgen.1005037. PMID: 25781991; PMCID: PMC4364372.
Edlund RK, Ohyama T, Kantarci H, Riley BB, Groves AK. Dev Biol. 2014 Jun 1;390(1):1-13. doi: 10.1016/j.ydbio.2014.03.004. Epub 2014 Mar 18. PMID: 24650709; PMCID: PMC4013273.
Vemaraju S, Kantarci H, Padanad MS, Riley BB. PLoS Genet. 2012;8(11):e1003068. doi: 10.1371/journal.pgen.1003068. Epub 2012 Nov 15. PMID: 23166517; PMCID: PMC3499369.