HUK, ALEXANDER C

Alexander C Huk

Professor
Department of Neuroscience, Department of Psychology


Focuses on how we see things move using electrophysiology, functional magnetic resonance imaging, psychophysics, and computational modeling.

huk@utexas.edu

Phone: 512-232-5729

Office Location
SEA 4.238

Postal Address
The University of Texas at Austin
Department of Neuroscience, College of Natural Sciences
1 University Station C7000
Austin, TX 78712

Postdoc, Physiology & Biophycs, University of Washington (2001-2004)

Ph.D., Stanford University (2001)

B.A., High Honors, Swarthmore College (1996)

Research Summary

Research in our lab focuses on how we see things move. We treat visual motion as a model system for investigating how the brain integrates information over space and time— as well as how these neural signals guide intelligent actions in a dynamic world.

Focusing our efforts within this framework allows us to study both the encoding and decoding of neural signals along a continuous pathway in the primate brain. In essence, we take an empirical perspective towards the underlying goal of understanding the neural code in cortex, i.e., what do action potentials and spike trains mean, given their location in the circuit and within a particular behavioral context?

The lab employs a variety of methods, including single-unit electrophysiology (with a current emphasis on multiple-neuron / multiple-area simultaneous recordings), functional magnetic resonance imaging, psychophysics, and computational modeling. 

Huk, A.C., Katz, L.N., Yates, J.L. (forthcoming). The role of the lateral intraparietal area in (the study of) decision making. Annual Review of Neuroscience[link]

Huk, A.C., Czuba, T.B., Knoell, J., & Cormack, L.K. (forthcoming). Binocular mechanisms of 3D motion processing. Annual Review of Vision Science[link

Joo, S.J., Czuba, T.B., Cormack, L.K., & Huk, A.C. (2016). Separate perceptual and neural processing of velocity- and disparity-based 3D motion signals. Journal of Neuroscience, 36 (42) 10791-10802[link]

Greer, D.A., Bonnen, K.T., Huk, A.C., Cormack L.K. (2016). Speed discrimination in the far monocular periphery: A relative advantage for interocular comparisons consistent with self-motion. Journal of Vision, 16(10):7, 1-12. [link]

Katz, L.N.*, Yates, J.L.*, Pillow, J.W., & Huk, A.C. (2016). Dissociated functional significance of decision-related activity in the primate dorsal stream. Nature, 535: 285–288. [link]

 

  • Spotlight in Trends in Neurosciences, Bijan Pesaran & David Freedman: [link]
  • Spotlight in Trends in Cognitive Sciences, Sashank Pisupati, Lital Chartarifsky, & Anne K. Churchland: [link]
  • Faculty of 1000 (F1000Prime) entry by Daeyeol Lee: [link]
  • Research Highlight in Nature Reviews Neuroscience: [link
  • Relevant review article in Current Opinion in Neurobiology, Carlos Brody & Tim Hanks [link]

 

Joo, S.J., Katz, L.N., & Huk, A.C. (2016). Decision-related perturbations of decision-irrelevant eye movements. Proceedings of the National Academy of Sciences, 113 (7): 1925-1930. [link]

Katz, L.N., Hennig, J., Cormack, L.K., & Huk, A.C. (2015). A distinct mechanism of temporal integration for motion through depth. Journal of Neuroscience, 35(28): 10212-10216. [link]

Latimer, K.W., Yates, J.L., Meister, M.L.R., Huk, A.C., & Pillow, J.W. (2015). Single-trial spike trains in parietal cortex reveal discrete steps during decision-making. Science, 349(6244): 184-187.  [link]

Goonetilleke, S.C., Katz L.N., Wood, D.K., Gu, C., Huk, A.C., & Corneil, B.D. (2015). Cross- species comparison of anticipatory and stimulus-driven neck muscle activity well before saccadic gaze shifts in humans and non human primates. Journal of Neurophysiology, 114(2): 902-913. [link]

Latimer, K.W., Huk, A.C., & Pillow, J. (2015). Bayesian inference for latent stepping and ramping models of spike train data. Chapter in Advanced State Space Methods for Neural and Clinical Data, Chen, Z, Ed., Cambridge University Press. [link]

Huk, A.C., Katz, L.N., & Yates, J.L. (2015). Accumulation of evidence in decision making. In Encyclopedia of Computational Neuroscience. Jaeger, D. & Jung, R., Eds., Springer[link]

Huk, A.C., & Joo, S.J. (2015).Motion perception. In Brain Mapping: An Encyclopedic Reference. Toga, A.W., Mesulam, M.M., & Kastner, S., Eds., Elsevier Press. [link]

Czuba, T.B., Huk, A.C., Cormack, L.K. & Kohn, A. (2014). Area MT encodes three-dimensional motion. Journal of Neuroscience, 34(47):15522–15533. [pdf]

 

  • Research Highlight in Nature Reviews Neuroscience [link]
  • Also see a related paper in the same issue by Sanada & Deangelis [link]

 

Park, I.M., Meister, M.L.R., Huk, A.C., & Pillow, J. (2014). Encoding and decoding in parietal cortex during sensorimotor decision-making. Nature Neuroscience, 17(10): 1395–1403.  [pdf]

Knudson, K., Yates, J., Huk, A., & Pillow, J. (2014). Inferring sparse representations of continuous signals with continuous orthogonal matching pursuit. In Advances in Neural Information Processing Systems, 27: 1215-1223. [pdf]

Meister, M.L.R., Hennig, J., & Huk, A.C. (2013). Signal multiplexing and single-neuron computations in macaque LIP during perceptual decision-making. Journal of Neuroscience, 33(6): 2254-2267. [pdf]

Huk, A.C., & Meister, M.L.R. (2012). Neural correlates and neural computations in posterior parietal cortex during perceptual decision-making. Frontiers in Integrative Neuroscience, 6:86. [pdf]

Huk, A.C. (2012). Multiplexing in the primate motion pathway. Vision Research, 62, 173-180. [pdf]

Czuba, T.B., Rokers, B., Huk, A.C., & Cormack, L.K. (2012). To CD or not to CD: Is there a motion aftereffect from changing disparities?Journal of Vision, 12(4):7, 1-3. [pdf]

Eastman, K.M. & Huk, A.C. (2012). PLDAPS: A hardware architecture and software toolbox for neurophysiology requiring complex visual stimuli and online behavioral control. Frontiers in Neuroinformatics, 6:1. doi: 10.3389/fninf.2012.00001 [pdf]

Czuba, T.B., Rokers, B., Guillet, K.R., Huk, A.C., & Cormack, L.K. (2011). 3D motion aftereffects reveal distinct direction-selective mechanisms for binocular processing of motion through depth. Journal of Vision, 11(10):18, 1-18. [pdf]

Rokers, B., Czuba, T.B., Cormack, L.K., & Huk, A.C. (2011). Seeing motion with two eyes in three dimensions. Journal of Vision, 11(2): 10. [pdf]

Czuba, T.B., Rokers, B., Huk, A.C., & Cormack, L.K. (2010). Speed and eccentricity tuning reveal a central role for the velocity-based cue to 3D motion. Journal of Neurophysiology, 104: 2886-2899. [pdf]

Winawer, J., Huk, A.C., & Boroditsky, L. (2010). A motion aftereffect from visual imagery of motion. Cognition, 114(2), 276-284. [pdf]

Rokers, B., Cormack, L.K., & Huk, A.C. (2009). Disparity- and velocity- based signals for 3D motion perception in human MT+. Nature Neuroscience, 12(8), 1050-1055. [pdf] [supplementary materials]

Ress, D., Thompson, J.K., Rokers, B., Khan, R., & Huk, A.C. (2009). A model for transient oxygen delivery in cerebral cortex. Frontiers in Neuroenergetics, 1:3. doi:10.3389/neuro.14.003.2009 [pdf] [online] [supplemental]

Wong, K-F., & Huk, A.C. (2008). Temporal dynamics underlying perceptual decision-making: Insights from the interplay between an attractor model and parietal neurophysiology. Frontiers in Neuroscience, 2(2), 245-254. [pdf]

Kirson, D., Huk, A.C., & Cormack, L.K. (2008). Quantifying spatial uncertainty of visual area boundaries in neuroimaging data. Journal of Vision, 8(10):10, 1-15. [pdf]

Huk, A.C. (2008). Visual neuroscience: Retinotopy meets percept-otopy? Current Biology, 18, R1005-1007. [pdf]

Rokers, B., Cormack, L.K., & Huk, A.C. (2008). Strong percepts of motion through depth without strong percepts of position in depth. Journal of Vision, 8(4):6, 1-10. [pdf] [online]

Winawer, J., Huk, A.C., & Boroditsky, L. (2008). A motion aftereffect from still photographs depicting motion. Psychological Science, 19, 276-283. [pdf]

Wong, K-F., Huk, A.C., Shadlen, M.N., & Wang, X-J. (2007). Neural circuit dynamics underlying accumulation of time-varying evidence during perceptual decision-making. Frontiers in Computational Neuroscience, 1:6. doi: 10.3389/neuro.10/006.2007 [pdf] [online]

Huk, A.C. & Shadlen, M.N. (2005). Neural activity in […] parietal cortex reflects temporal integration of visual motion signals during perceptual decision making. Journal of Neuroscience, 25, 10420-10436. [pdf]

Palmer, J., Huk, A.C., & Shadlen, M.N. (2005). The effect of stimulus strength on the speed and accuracy of a perceptual decision. Journal of Vision, 5, 376-404. [pdf]

Huk, A.C., Dougherty, R.F., & Heeger, D.J. (2002). Retinotopy and functional subdivision of human areas MT and MST. Journal of Neuroscience, 22, 7195-7205. [pdf]

Huk, A.C., & Heeger, D.J. (2002). Pattern-motion responses in human visual cortex. Nature Neuroscience, 5, 72-75. [pdf]

Huk, A.C., Ress, D., & Heeger, D.J. (2001). Neuronal basis of the motion aftereffect reconsidered. Neuron, 32, 161-172. [pdf]

Heeger, D.J., Gandhi, S.P., Huk, A.C., & Boynton, G.M. (2001). Neuronal correlates of attention in human visual cortex. In J. Braun, C. Koch, & J. Davis (Eds.), Visual Attention and Cortical Circuits, pp. 25-47. Cambridge, MA: MIT Press. [pdf]

Huk, A.C., & Heeger, D.J. (2000). Task-related modulation of visual cortex. Journal of Neurophysiology, 83, 3525-3536. [pdf]

Heeger, D.J., Huk, A.C., Geisler, W.S., & Albrecht, D.G. (2000). Spikes versus BOLD: What does neuroimaging tell us about neuronal activity? Nature Neuroscience, 3, 631-633. [pdf]

Wandell, B.A., Poirson, A.A., Baseler, H.A., Boynton, G.M., Huk, A.C., Gandhi, S.P., & Sharpe, L.T. (1999). Color signals in human motion-selective cortex. Neuron, 24, 901-909. [pdf]

Durgin, F.H., & Huk, A.C. (1997). Texture density aftereffects in the perception of artificial and natural textures. Vision Research, 37, 3273-3282. [pdf]

  • National Science Foundation CAREER Award
  • Elsevier / Vision Sciences Society Young Investigator Award, 2011.
  • Teaching Excellence Award, College of Natural Sciences, UT-Austin, 2009.